Loading...
Long-term retinal oximetry and OCT angiography in patients recovered from COVID-19.
Šindelářová, Barbora Šín, Martin
Šindelářová, Barbora
Šín, Martin
Abstract
The aim of this study was to analyse retinal microvascular abnormalities in patients with various degrees of severity of the course of Coronavirus Disease 2019 (COVID-19), with a focus on patients requiring extracorporeal membrane oxygenation (ECMO) or mechanical ventilation (MV). We subclassified the patients after COVID-19 into 3 groups based on the severity of the disease and then performed standard ophthalmic examination, optical coherence tomography (OCT), macular OCT angiography (OCT-A) and retinal oximetry (RO). A total of 32 patients (21 men and 11 women; mean age of 51 years) were included in the study. Group 1 (mild COVID-19 course) included 11 patients, group 2 (moderate course) included 8 patients, and group 3 (severe course) included 13 patients which is particularly noteworthy. The median time after COVID-19 recovery was 22 months. No statistically significant difference between the groups was detected in any of the parameters of interest, suggesting resilience of retinal vasculature post-COVID-19. Patients after full recovery from severe COVID-19 do not show any significant decrease in oxygen saturation of retinal vessels 1.5 years (median) after the episode. Our data show that even a severe course of COVID-19 with ECMO or MV does not cause chronic microvascular changes in the retina.
Description
Keywords
Coronavirus disease 19, Extracorporeal membrane oxygenation, Mechanical ventilation, Optical coherence angiography, Oxymap, Retinal oximetry
Funding
Related Items
Research Projects
Organizational Units
Journal Issue
Collections
Files
Type
License
Attribution 4.0 International
Date
2025-10-29
Publisher
Nature Portfolio
Book
Journal
Scientific Reports
item.page.journal.issn
item.page.volume.title
DOI
10.1038/s41598-025-21794-w
Citation
Schreiberová, Z., Genzor, S., Mudroch, T., Šindelářová, B., Hübnerová, P., Malušková, M., Marešová, K., Šín, M., & Karhanová, M. (2025). Long-term retinal oximetry and OCT angiography in patients recovered from COVID-19. Scientific Reports, 15(1), 37851. https://doi.org/10.1038/s41598-025-21794-w